Fig. 2

Brain MRI, histopathology and PCR result of case 5. a–c Images were obtained before operation. Solitary brain mass lesion (white arrows), with perifocal edema (yellow arrows), ring and nodular accumulation patterns of the contrast agent (blue arrow). d, f Images were obtained 10 days after the operation. Residual cavity after operation (white arrows), perifocal edema reduced significantly (yellow arrows). g One new-onset lesion at contralateral side of frontal lobe after the operation 10 days later (white arrow). h Images were obtained after 4 weeks of anti-Toxoplasma therapy. Brain lesion of new-onset almost disappeared, the patient’s clinical condition obviously improved after 4 weeks of anti-Toxoplasma therapy. His OS was 191 days, the seizure never attacked again. i–k Photomicrograph of the histopathological TE, hematoxylin-eosin stained (100×), necrotic center (i), intermediate zone (j), peripheral zone (k) (not contained the encysted form of TG). l The RT-PCR of BML revealed-TG positivity