Table 2 Selected proteins downregulated at 6 or 48 h post-R. rickettsii infection of BME26 cells
Functional class of proteins | 6 h post-infection | 48 h post-infection | ||
|---|---|---|---|---|
ID | Annotation | ID | Annotation | |
ST/ APOPTOSIS | BME26USP-3827 | Mucin-1—Negative regulation of intrinsic apoptotic signaling pathway in response to DNA damage by p53 class mediator | – | – |
BME26USP-65523 | Apoptosis inhibitor 5/fibroblast growth factor 2-interacting factor 2 | |||
BME26USP-74870 | Clathrin assembly protein AP180 | |||
BME26USP-4568 | Ubiquinone oxidoreductase b16.6 subunit/cell death | |||
PROT | BME26USP-65609 | 20S Proteasome regulatory subunit beta type PSMB4/PRE4 | BME26USP-65272 | SCF ubiquitin ligase Skp1 component |
BME26USP-64301 | 26S Proteasome regulatory complex ATPase RPT6 | |||
BME26USP-75557 | 20S Proteasome regulatory subunit alpha type PSMA2/PRE8 | |||
BME26USP-4899 | 20S Proteasome regulatory subunit beta type PSMB1/PRE7 | |||
BME26USP-77519 | 26S Proteasome regulatory complex subunit RPN10/PSMD4 | |||
BME26USP-23319 | ATP-dependent Lon protease | |||
CS | BME26USP-75222 | Alpha tubulin | BME26USP-26191 | Protein tyrosine kinase |
BME26USP-71918 | Actin-related protein Arp2/3 complex subunit Arp2 | |||
BME26USP-62031 | Cdc42 homolog/positive regulation of protein kinase/maintenance of protein location/adherens junction | |||
BME26USP-2688 | GDP dissociation inhibitor/microtubule-associated complex/protein transport/Rab GDP-dissociation inhibitor | BME26USP-SigP-76633 | Tyrosine kinase eph ephrin receptor family | |
BME26USP-4897 | Actin-related protein Arp2/3 complex subunit ARPC1/p41-ARC | |||
BME26USP-25990 | Dynein light intermediate chain | |||
BME26USP-77773 | Microtubule-actin cross-linking factor 1 | |||