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Table 2 Selected proteins downregulated at 6 or 48 h post-R. rickettsii infection of BME26 cells

From: The intracellular bacterium Rickettsia rickettsii exerts an inhibitory effect on the apoptosis of tick cells

Functional class of proteins 6 h post-infection 48 h post-infection
ID Annotation ID Annotation
BME26USP-3827 Mucin-1—Negative regulation of intrinsic apoptotic signaling pathway in response to DNA damage by p53 class mediator
BME26USP-65523 Apoptosis inhibitor 5/fibroblast growth factor 2-interacting factor 2
BME26USP-74870 Clathrin assembly protein AP180
BME26USP-4568 Ubiquinone oxidoreductase b16.6 subunit/cell death
PROT BME26USP-65609 20S Proteasome regulatory subunit beta type PSMB4/PRE4 BME26USP-65272 SCF ubiquitin ligase Skp1 component
BME26USP-64301 26S Proteasome regulatory complex ATPase RPT6
BME26USP-75557 20S Proteasome regulatory subunit alpha type PSMA2/PRE8
BME26USP-4899 20S Proteasome regulatory subunit beta type PSMB1/PRE7
BME26USP-77519 26S Proteasome regulatory complex subunit RPN10/PSMD4
BME26USP-23319 ATP-dependent Lon protease
CS BME26USP-75222 Alpha tubulin BME26USP-26191 Protein tyrosine kinase
BME26USP-71918 Actin-related protein Arp2/3 complex subunit Arp2
BME26USP-62031 Cdc42 homolog/positive regulation of protein kinase/maintenance of protein location/adherens junction
BME26USP-2688 GDP dissociation inhibitor/microtubule-associated complex/protein transport/Rab GDP-dissociation inhibitor BME26USP-SigP-76633 Tyrosine kinase eph ephrin receptor family
BME26USP-4897 Actin-related protein Arp2/3 complex subunit ARPC1/p41-ARC
BME26USP-25990 Dynein light intermediate chain
BME26USP-77773 Microtubule-actin cross-linking factor 1
  1. ST/apoptosis: signal transduction and apoptosis; PROT: proteasome machinery; CS: cytoskeletal functional classes, SCF, Skp1/Cullin/F-box containing complex