Skip to main content

Table 1 Transcripts differentially expressed between wild-type and SbIII-resistant L. infantum lines and Gene Ontology (GO) functional enrichment analysis

From: Comparative transcriptomic analysis of antimony resistant and susceptible Leishmania infantum lines

  GO category: biological process GO category: cellular component or molecular function Without GO Total
Enriched Not enriched
Functional annotationa
 Upregulated 111 (11.90%) 13 (1.39%) 289 (31.94%) 18 (1.93%) 431 (46.19%)
 Downregulated 37 (3.96%) 0 6 (0.64%) 30 (3.21%) 73 (7.82%)
Hypothetical proteinsb
 Upregulated 32 (3.43%) 13 (1.39%) 142 (15.22%) 219 (23.47%) 406 (43.51%)
 Downregulated 1 (0.11%) 0 0 22 (2.36%) 23 (2.79%)
Total number of DE transcripts identified 181 26 437 289 933
  1. aTranscripts with functional annotation
  2. bTranscripts with no assigned function