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Table 2 Upregulated enriched genes associated to the Gene Ontology biological process category

From: Comparative transcriptomic analysis of antimony resistant and susceptible Leishmania infantum lines

ID

Description

Fold change

P-value

Protein phosphorylation

 LINF_320013700

CYC2-like cyclin—putativea

5.56

3.34E−42

 LINF_340027100

Dual specificity protein phosphatase—putative

8.93

4.34E−107

 LINF_360054700

Elongation factor-2 kinase-like protein

3.23

2.10E−16

 LINF_350046100

Kinetoplastid kinetochore protein 3—putative

2.02

9.69E−13

 LINF_250012200

Myosin heavy chain kinase c-like protein

3.37

3.77E−20

 LINF_300023300

Phosphatidylinositol kinase—putativea

3.97

4.10E−42

 LINF_360034100

Protein kinase—putativea

3.88

5.44E−42

 LINF_010011100

Rab-GTPase-TBC domain-containing protein

2.13

1.17E−16

 LINF_340047100

Target of rapamycin kinase 3a

2.74

2.33E−21

Microtubule-based movement

 LINF_070010300

Dynein heavy chaina

5.90

6.51E−54

 LINF_130011900

Kinesin—putativea

5.87

1.11E−70

 LINF_330038800

Present in the outer mitochondrial membrane

4.06

1.74E−37

 LINF_260024800

Microtubule-associated protein—putative

3.73

1.67E−59

 LINF_270017700

Intraflagellar transport protein 88—putative

2.16

2.53E−19

 LINF_040010500

Tetratricopeptide repeat

2.14

2.06E−19

 LINF_210017400

WD40 repeat-containing protein

2.06

4.35E−21

Biosynthetic process

 LINF_350008300

Serine palmitoyltransferase—putative

2.99

2.23E−35

 LINF_170011100

Phenazine biosynthesis-like protein

2.15

3.76E−08

Cellular process

 LINF_360020600

N-terminal region of chorein

4.95

3.27E−59

 LINF_190015000

FYVE zinc finger-containing protein

3.66

2.95E−27

 LINF_270009800

Glycosomal transporter (GAT3)—putative

3.39

1.48E−39

 LINF_240020050

Multi-drug resistance protein-like

3.27

1.11E−33

 LINF_350025400

Ankyrin repeat protein—putative

2.67

1.11E−21

Cellular component organization

 LINF_130020500

Phosphoprotein phosphatase—putative

2.28

1.71E−11

Protein ubiquitination

 LINF_350059500

SPRY domain; HECT-domain (ubiquitin-transferase)a

9.14

4.18E−81

 LINF_360053000

Ubiquitin protein ligase—putativea

7.30

3.59E−111

 LINF_220017000

Zinc finger—C3HC4 type (RING finger)

3.77

2.20E−40

 LINF_110017600

Protein transport protein SEC31—putative

3.57

6.80E−54

 LINF_160017100

WW domain-containing protein

2.63

5.06E−15

 LINF_160018000

Cullin family

2.23

1.06E−15

Ribonucleoprotein complex assembly

 LINF_170016300

ATP-dependent RNA helicase—putative

2.38

1.49E−26

Stress granule assembly

 LINF_180019600

Pumilio protein 2—putative

5.59

6.98E−64

Cellular metabolic process

 LINF_270018400

RING-H2 zinc finger

3.33

9.20E−24

 LINF_290018600

Heat shock protein 100 kDa

2.86

5.67E−32

Primary metabolic process; cellular macromolecule biosynthetic process; cellular nitrogen compound metabolic process

 LINF_300022800

DNAJ domain protein—putative

2.13

9.30E−14

Primary metabolic process; macromolecule metabolic process; nitrogen compound metabolic process

 LINF_120008300

Myotubularin-related protein—putative

4.00

4.38E−52

Multi-organism cellular process

 LINF_310038500

Acetyl-CoA carboxylase—putative

2.74

5.28E−33

Regulation of membrane lipid distribution; phospholipid translocation

 LINF_340032300

Phospholipid-transporting ATPase-like proteina

3.69

2.87E−39

Regulation of membrane lipid distribution

 LINF_260032600

ATP-binding cassette protein subfamily B—member 2—putative

2.21

7.28E−13

Quorum sensing involved in interaction with host; multi-organism cellular process; modulation of symbiont involved in interaction with host

 LINF_330022900

RNA recognition motif. (a.k.a. RRM–RBD or RNP domain)a

14.4

1.07E−153

 LINF_330023000

RNA-binding protein—putative

4.01

1.25E−12

  1. aGenes with more than one copy in the corresponding GO category. See Additional file 1: Table S1 for complete data