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Fig. 5 | Parasites & Vectors

Fig. 5

From: Endochin-like quinolone-300 and ELQ-316 inhibit Babesia bovis, B. bigemina, B. caballi and Theileria equi

Fig. 5

Percentage of cell viability over a period of 72 h after incubation with the IC50 and IC100of ELQ-300 and ELQ-316. Cells+Med Peripheral blood mononuclear cells (PBMC) cultivated without the addition of the ELQ compounds. Cells in cultured in DMSO and Draxxin® were used as a negative control; concanavalin A (ConA) was used as a positive control for cell proliferation. a Bovine PBMC, b horse PBMC. Bovine and horse PBMC assays were carried out in triplicate and the error bars indicate standard error deviation. Asterisk (*) represents statistically significant differences compared to PBMC cultivated in medium only at P < 0.05, using Student’s t-test

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