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Fig. 1 | Parasites & Vectors

Fig. 1

From: IPSE, a urogenital parasite-derived immunomodulatory molecule, suppresses bladder pathogenesis and anti-microbial peptide gene expression in bacterial urinary tract infection

Fig. 1

H-IPSE does not affect bacteriuria in mice. “PBS-UTI”: mice given PBS vehicle tail vein injections prior to UTI challenge; “H-IPSE+UTI”: mice administered the H06 ortholog of IPSE before UTI challenge; “H-IPSENLS-+UTI”: mice given a nuclear localization sequence mutant of the H06 ortholog of IPSE prior to UTI challenge. Bars represent mean and standard deviation. Data are pooled from two independent experiments with each symbol representing an individual mouse’s urine CFU at the indicated point in time. Mice receiving H-IPSENLS were only sampled until day 5 post-infection, whereas all other mice were sampled until day 7. Observations were not determined to be statistically significant

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Parasites & Vectors

ISSN: 1756-3305

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