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Table 2 Haematological reference intervals for healthy bare-nosed and southern hairy-nosed wombats obtained from the literature together with the mean, minimum and maximum values obtained from healthy bare-nosed wombats at all time points during the 25 mg/kg and 85 mg/kg trials

From: Fluralaner as a novel treatment for sarcoptic mange in the bare-nosed wombat (Vombatus ursinus): safety, pharmacokinetics, efficacy and practicable use

Haematological parameter

Reference interval

25 mg/kg trial (n = 5)

85 mg/kg trial (n = 2)

BNW

SHNW

Mean

Min–max

Mean

Min–max

Red blood cells (×1012/l)

3.9–7.0

4.2–6.2

4.9

3.3–6.1

5.2

4.5–5.9

Haemoglobin (g/l)

77.6–168.6

108.8–163.6

123.2

80.0–153.0

124.2

113.0–136.0

Haematocrit (l/l)

0.3–0.5

–

0.4

0.2–0.5

0.4

0.3–0.4

Mean corpuscular volume (fl)

65.0–83.8

76.5–87.5

76a

70.0–86.0

70.4a

66.0–74.0

Mean corpuscular haemoglobin (pg)

12.7–32.3

24.1–28.9

25.4a

24.0–28.0

24.0a

22.0–26.0

Mean cell haemoglobin concentration (g/l)

288.7–377.1

299.3–343.9

333.8

303.0–357.0

340.9

321.0–358.0

White blood cells (× 109/l)

0.9–19.7

0–18.7

9.1

4.7–15.3

8.6

6.3–11.2

Neutrophils (× 109/l)

0.8–10.5

0–15.9

4.4

1.0–9.4

3.6

2.2–6.5

Lymphocytes (× 109/l)

0.0–14.7

0–3.4

3.9

1.5–8.7

4.3

1.8–7.7

Monocytes (× 109/l)

0.0–1.3

0–1.3

0.5

0.0–2.1

0.5

0.0–1.6

Eosinophils (× 109/l)

0.0–1.7

0–1.5

0.3

0.0–1.1

0.2

0.0–0.4

  1. Parameters that deviated from reference intervals for bare-nosed or southern-hairy nosed wombats are highlighted in italics
  2. aSignificant change observed over time-post fluralaner administration