The leishmanicidal effect of Lucilia sericata larval saliva and hemolymph on in vitro Leishmania tropica

Parasites & Vectors

Table 3 Effect of Lucilia sericata larval-derived products on Leishmania tropica amastigote in in vitro conditions

Treatment	Dosages (µg/ml)	Amastigote L. tropica/peritoneal cell				Amastigote L. tropica/J774 cell line
Treatment		I%		V%		I%		V%
Time (h)		72 h	120 h	72 h	120 h	72 h	120 h	72 h	120 h
No treatment control	0	79.3 ± 4.7	72.3 ± 4.7	100 ± 0	100 ± 0	66.3 ± 4	59 ± 3.6	100 ± 0	100 ± 0
Saliva	150	69 ± 4	58.3 ± 3.5	74.2 ± 2	53.1 ± 2.3	58 ± 4	35 ± 2.6	67.5 ± 3.2	48.7 ± 3.3
Saliva	450	57 ± 3.6	46 ± 3	69.5 ± 2.7	47.7 ± 3.1	51.3 ± 1.5	26.3 ± 2.5	62.4 ± 3.2	39 ± 3.8
Hemolymph	150	63.3 ± 2.5	50.3 ± 3.2	64.5 ± 3	42.8 ± 3.4	56 ± 4.4	22 ± 4	56.6 ± 3.9	38.4 ± 2
Hemolymph	450	50.7 ± 4	34.3 ± 4.7	57.7 ± 4	35.9 ± 2.8	40.3 ± 3.1	15 ± 3	48.7 ± 2.6	26.6 ± 2.8
Positive control	50	57 ± 1	44 ± 4	66.9 ± 2.7	49.3 ± 2.8	47.3 ± 3.8	27.3 ± 2.5	60.3 ± 2.7	45.7 ± 1.9
Glucantime	100	48 ± 2	36.3 ± 5.1	55.4 ± 2.5	35.7 ± 3.1	36 ± 2.6	13.3 ± 3.2	46.2 ± 4	34 ± 3.3

ISSN: 1756-3305