Molecular characterization of RNase III protein of Asaia sp. for developing a robust RNAi-based paratransgensis tool to affect the sexual life-cycle of Plasmodium or Anopheles fitness

Table 3 Validation of the three predicted 3D models of Asaia RNase III model with ProSA and TM-score

Asaia RNase III model	QMEAN	ProSA^a	TM-score^b
Asaia RNase III model	QMEAN	Z-score	4M30	Swiss-model	Phyre2	Modeller
Swiss-model	− 4.44	− 5.54	0.899	–	0.55	0.81
Phyre2	− 3.37	− 5.52	0.531	0.55	–	0.56
Modeller	− 3.83	− 5.64	0.7732	0.81	0.56	–

^aPRoSA Z-score determines the overall model quality
^bTM-score has the value in (0, 1]. Higher score indicates generally the same folding

ISSN: 1756-3305