Fig. 5
Conditional knockdown of PfSWIB leads to a change in mutually exclusive var gene transcription in a single 48-h life-cycle. qPCR analysis of the transcription level of individual var genes in three lines during a single 48-h life-cycle of P. falciparum. The data are presented as log2 fold change of trophozoite to ring within the third life-cycle, using the seryl-tRNA synthetase gene (PF3D7_0717700) as an endogenous control. The error bars represent the mean ± SD of three independent experiments. The red, green and blue bars in the histogram represent upsA-, upsB- and upsC- type vars, respectively