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Table 3 Tests for selection in Pvmdr1 genes from parasite populations from the China–Myanmar border and central China

From: Evolution of the Plasmodium vivax multidrug resistance 1 gene in the Greater Mekong Subregion during malaria elimination

Populations

Z-test (dN-dS)

MacDonald & Kreitman test

Alpha-value

G-value

China–Myanmar border 2008 (n = 27)

− 1.094

− 0.554

0.976

China–Myanmar border 2012–2013 (n = 129)

− 0.850

− 2.003*

20.580***

China–Myanmar border 2015 (n = 119)

− 1.481

− 1.800***

21.470***

Central China 2004–2008 (n = 55)

− 0.304

− 1.566

4.262*

  1. *P < 0.05, ***P < 0.001