Skip to main content

Advertisement

Table 4 Arithmetic mean flea and egg counts and percent efficacy relative to placebo after treatment and weekly re-infestations with Ctenocephalides felis for dogs treated orally with Simparica Trio™ (Study 5)

From: Laboratory studies evaluating the efficacy of a novel orally administered combination product containing sarolaner, moxidectin and pyrantel (Simparica Trio™) for the treatment and control of flea infestations on dogs

Day after treatmentTreatment groupFlea count% EfficacyEgg count% Efficacy
1Placebo73.8 364.0 
Simparica Trio™0*1000100
7Placebo71.7 444.5 
Simparica Trio™0*1000100
14Placebo67.0 496.2 
Simparica Trio™0*1000100
21Placebo61.5 488.5 
Simparica Trio™0*1000100
28Placebo60.8 440.6 
Simparica Trio™0*1000100
35Placebo63.6 366.8 
Simparica Trio™0*1000100
  1. *Flea counts are significantly lower than placebo; 10.09 ≤ t(9) ≤ 41.72, P < 0.0001