Table 6 Efficacy of a single oral dose of Simparica Trio™ and afoxolaner+ milbemycin oxime against natural infestations with Ixodes ricinus, Rhipicephalus sanguineus, Dermacentor reticulatus and Ixodes hexagonus on dogs presented as veterinary patients in Europe
Treatment group | Study day | I. ricinus | R. sanguineus | D. reticulatus | I. hexagonus | ||||
|---|---|---|---|---|---|---|---|---|---|
Mean tick count | % Efficacy | Mean tick count | % Efficacy | Mean tick count | % Efficacy | Mean tick count | % Efficacy | ||
Simparica Trio™ | − 1 or 0 | 3.5 | – | 13.7 | – | 1.8 | – | 1.0 | – |
7 ± 2 | 0.1 | 99.1 | 1.1 | 96.6 | 0 | 100 | 0 | 100 | |
14 ± 2 | 0.1 | 98.8 | 0.8 | 93.9 | 0 | 100 | 0 | 100 | |
21 ± 2 | 0.1 | 99.1 | 0.2 | 97.2 | 0 | 100 | 0 | 100 | |
30 ± 4 | 0 | 100.0 | 0.2 | 97.0 | 0 | 100 | 0 | 100 | |
Afoxolaner + Milbemycin oxime | − 1 or 0 | 3.3 | – | 15.3 | – | 2.0 | – | 2.7 | – |
7 ± 2 | 0.3 | 95.2 | 0.9 | 97.8 | 0 | 100 | 0 | 100 | |
14 ± 2 | 0.1 | 96.9 | 0.6 | 97.9 | 0 | 100 | 0 | 100 | |
21 ± 2 | 0.1 | 96.4 | 0.1 | 99.3 | 0 | 100 | 0 | 100 | |
30 ± 4 | 0 | 99.5 | 0.3 | 99.1 | 0 | 100 | 0 | 100 | |