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Fig. 3 | Parasites & Vectors

Fig. 3

From: Evaluation of in vitro antileishmanial efficacy of cyclosporin A and its non-immunosuppressive derivative, dihydrocyclosporin A

Fig. 3

Ultrathin sections of promastigotes. Untreated control promastigotes (a) and promastigotes treated with CsA (16 μM) (b), DHCsA-d (12 μM) (c), or SSG (20 μM) (d) for 48 h. There were several alterations observed, such as changes in the shape of the promastigotes and mitochondria (b–d): the promastigotes became rounded and mitochondria became rounded and swollen and several lipid bodies were present (b, c) and multiple flagellum (c). Abbreviations: F, flagellum; GC, Golgi complex; K, kinetoplast; LB, lipid bodies; M, mitochondrion; N, nucleus

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