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Table 2 Statistical tests for cytokines, NO and H2O2

From: Evaluation of in vitro antileishmanial efficacy of cyclosporin A and its non-immunosuppressive derivative, dihydrocyclosporin A

 24 h48 h72 h
IL-12N vs I-L. DD8t(12) = 2.4285
P = 0.0318
t(12) = 2.9252
P = 0.0127
t(12) = 2.87
P = 0.0141
I-L. DD8 + CsA vs I-L. DD8t(12) = 0.8554
P = 0.4149
t(12) = 0.9571
P = 0.3567
t(12) = 1.4637
P = 0.1689
I-L. DD8 + DHCsA-d vs I-L. DD8t(12) = 9.7045
P < 0.0001
t(12) = 8.2368
P < 0.0001
t(12) = 7.3545
P < 0.0001
I-L. DD8 + SSG vs I-L. DD8t(12) = 9.6968
P < 0.0001
t(12) = 8.7509
P < 0.0001
t(12) = 7.4532
P < 0.0001
IFN-γN vs I-L. DD8t(12) = 2.3545
P = 0.0364
t(12) = 3.5317
P = 0.0041
t(12) = 4.4146
P = 0.0008
I-L. DD8 + CsA vs I-L. DD8t(12) = 1.0839
P = 0.2997
t(12) = 1.0695
P = 0.3059
t(12) = 0.7226
P = 0.4838
I-L. DD8 + DHCsA-d vs I-L. DD8t(12) = 23.9059
P < 0.0001
t(12) = 22.2593
P < 0.0001
t(12) = 19.4494
P < 0.0001
I-L. DD8 + SSG vs I-L. DD8t(12) = 21.4421
P < 0.0001
t(12) = 20.7228
P < 0.0001
t(12) = 19.7626
P < 0.0001)
TNF-αN vs I-L. DD8t(12) = 2.3822
P = 0.0346
t(12) = 3.8117
P = 0.0025
t(12) = 4.3674
P = 0.0009
I-L. DD8 + CsA vs I-L. DD8t(12) = 2.0144
P = 0.0669
t(12) = 2.1263
P = 0.0549
t(12) = 1.9025
P = 0.0814
I-L. DD8 + DHCsA-d vs I-L. DD8t(12) = 11.3431
P < 0.0001
t(12) = 10.1318
P < 0.0001
t(12) = 9.2065
P < 0.0001
I-L. DD8 + SSG vs I-L. DD8t(12) = 12.1475
P < 0.0001
t(12) = 10.9044
P < 0.0001
t(12) = 9.4807
P < 0.0001
IL-10N vs I-L. DD8t(12) = 17.7485
P < 0.0001
t(12) = 17.021
P < 0.0001
t(12) = 16.7054
P < 0.0001,
I-L. DD8 + CsA vs I-L. DD8t(12) = 1.6069
P = 0.134
t(12) = 1.6572
P = 0.1234
t(12) = 0.8703
P = 0.4012
I-L. DD8 + DHCsA-d vs I-L. DD8t(12) =11.2823
P < 0.0001
t(12) = 11.3959
P < 0.0001
t(12) = 12.8072
P < 0.0001
I-L. DD8 + SSG vs I-L. DD8t(12) =11.9725
P < 0.0001
t(12) = 12.1698
P < 0.0001
t(12) = 13.2122
P < 0.0001
IL-4N vs I-L. DD8t(12) = 11.8592
P < 0.0001
t(12) = 11.2109
P < 0.0001
t(12) = 9.6496
P < 0.0001
I-L. DD8 + CsA vs I-L. DD8t(12) = 1.1525
P = 0.2715
t(12) = 1.3592
P = 0.1991
t(12) = 1.4827
P = 0.1639
I-L. DD8 + DHCsA-d vs I-L. DD8t(12) = 6.8682
P < 0.0001
t(12) = 6.4039
P < 0.0001
t(12) = 5.8037
P < 0.0001
I-L. DD8 + SSG vs I-L. DD8t(12) = 8.1166
P < 0.0001
t(12) = 7.9485
P < 0.0001
t(12) = 6.6847
P < 0.0001
NON vs I-L. DD8t(12) = 14.8865
P < 0.0001
t(12) = 11.2109
P < 0.0001
t(12) = 8.9723
P < 0.0001
I-L. DD8 + CsA vs I-L. DD8t(12) = 0.6153
P = 0.5498
t(12) = 0.6931
P = 0.5015
t(12) = 0.5985
P = 0.5606
I-L. DD8 + DHCsA-d vs I-L. DD8t(12) = 7.7965
P < 0.0001
t(12) = 5.8653
P < 0.0001
t(12) = 4.72
P = 0.0004
I-L. DD8 + SSG vs I-L. DD8t(12) = 7.7822
P < 0.0001
t(12) = 5.6942
P = 0.0001
t(12) = 3.8402
P = 0.0024
H2O2N vs I-L. DD8t(12) = 4.6596
P = 0.0006
t(12) = 5.3572
P = 0.0002
t(12) = 3.3676
P = 0.0056
I-L. DD8 + CsA vs I-L. DD8t(12) = 0.9975
P = 0.3382
t(12) = 1.222
P = 0.2452
t(12) = 0.7519
P = 0.4666
I-L. DD8 + DHCsA-d vs I-L. DD8t(12) = 4.6618
P = 0.0005
t(12) = 5.405
P = 0.0002
t(12) = 3.4004
P = 0.0053
I-L. DD8 + SSG vs I-L. DD8t(12) = 4.6047
P = 0.0006
t(12) = 5.2354
P = 0.0002
t(12) = 3.0176
P = 0.0107
  1. Abbreviations: N, non-infected macrophages; I-L. DD8, macrophages infected with L. DD8; I-L. DD8 + SSG, SSG adding after macrophages infected with L. DD8; I-L. DD8 + CsA, CsA adding after macrophages infected with L. DD8; I-L. DD8 + DHCsA-d, DHCsA-d adding after macrophages infected with L. DD8