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Table 3 CC50 of CsA, DHCsA-d, or SSG used for treatment of RAW 264.7 cells

From: Evaluation of in vitro antileishmanial efficacy of cyclosporin A and its non-immunosuppressive derivative, dihydrocyclosporin A

CompoundCytotoxicity (RAW 264.7) CC50
24 h48 h
Mean ± SD (µM)Mean ± SD (µM)
CsA15.91 ± 0.212.65 ± 1.2
DHCsA-d7.98 ± 0.46.65 ± 0.7
SSG> 120> 120
  1. Note: Data are represented as the mean ± SD of three independent experiments
  2. Abbreviations: CC50, 50% cytotoxic concentration; SD, standard deviation