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Table 3 CC50 of CsA, DHCsA-d, or SSG used for treatment of RAW 264.7 cells

From: Evaluation of in vitro antileishmanial efficacy of cyclosporin A and its non-immunosuppressive derivative, dihydrocyclosporin A

Compound

Cytotoxicity (RAW 264.7) CC50

24 h

48 h

Mean ± SD (µM)

Mean ± SD (µM)

CsA

15.91 ± 0.2

12.65 ± 1.2

DHCsA-d

7.98 ± 0.4

6.65 ± 0.7

SSG

> 120

> 120

  1. Note: Data are represented as the mean ± SD of three independent experiments
  2. Abbreviations: CC50, 50% cytotoxic concentration; SD, standard deviation
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Parasites & Vectors

ISSN: 1756-3305

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