Fig. 5

Promastigote infectivity of both WT parent and derived counterparts that were repeatedly exposed to MIL either in vitro (a) or in vivo (b). No significant differences in in vitro macrophage infectivity are observed. Maximum infectivity was reached with 168 h-old cultures for BPK275/0-cl18 and with 192 h/216 h-old cultures for BPK282/0-cl4. Results are expressed as the mean infection index ± SE and are based on three independent replicates