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Table 1 Results of the faecal egg count reduction (FECR) after treatment with different doses of albendazole and the 50% effective concentration (EC50) in the egg hatch test for goats naturally infected with gastrointestinal nematodes or experimentally infected with local Haemonchus contortus isolates at Rehed Al-Birdi, Tulus and Um Dafuq (South Darfur, Sudan)

From: New codon 198 β-tubulin polymorphisms in highly benzimidazole resistant Haemonchus contortus from goats in three different states in Sudan

Study areaInfection typeGI nematodesDose (mg/kg bw)No. of animals in each trialDay 8Day 14EC50 (µg/ml thiabendazole)
FECR (%)
Unpaireda
FECR (%)
Paireda
FECR (%)
Unpaireda
FECR (%)
Paireda
Rehed Al-BirdiNaturalStrongyles5C: n = 893.3 (82.1–97.7)94.1 (92.4–95.6)87.5 (68.5–94.9)90.2 (88.3–91.8)0.08 (0.03–0.24)
T: n = 8
Strongyles7.5C: n = 1392.1 (80.5–96.6)95.6 (94.8–96.3)87.1 (72.8–94.4)93.7 (92.9–94.5) 
T: n = 10
Strongyles10C: n = 1390.4 (82–95.2)92.2 (91.5–93)86.5 (71.8–93.1)89.8 (88.9–90.7) 
T: n = 25
Strongyles12.5C: n = 1397.1 (93.4–98.8)97.5 (96.7–98)96.6 (89.9–98.8)97.2 (96.4–97.8) 
T: n = 13
TulusNaturalStrongyles5C: n = 1192 (86.1–95.2)94.6 (94.1–95)85.8 (72.1–93.4)88.5 (87.8–89.1)0.08 (0.07–0.1)
T: n = 27
5Rb: n = 12na64.5 (60.2–68.4)na54.4 (49.8–59.4) 
10C: n = 1189.9 (76.1–95.2)90 (88.7–91.2)89.6 (65.5–96.2)87.3 (85.8–88.7) 
T: n = 12
Experi-mentalH. contortus5C: n = 885.2 (60.1–93.5)86.2 (84.7–87.5)76.3 (34.1–91.9)81.8 (79.9–83.4)0.11 (0.08–0.16)
T: n = 8
Um DafuqExperi-mentalH. contortus5C: n = 890.9 (80.2–94.8)84.2 (82.9–85.5)82.8 (57–90.8)73.5 (72–75.4)0.11 (0.07–0.17)
T: n = 8
  1. aFECRs were calculated either by comparing data post-treatment between treatment and control group (unpaired) or between data post- and pre-treatment (paired); 95% confidence interval is provided in parentheses
  2. bRetreated goats were initially treated first with 5 mg/kg albendazole and received a repeated dose of albendazole (5 mg/kg body weight) on day 14
  3. Abbreviations: bw, body weight; C, control; T, treated; R, retreated; na, no control group available since the treated group was retreated for the second time