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Table 1 Activity of peroxide dismutase, catalase, glutathione peroxidase, glutathione reductase and glutathione reductase in eye samples of immunocompetent and immunosuppressed infected and uninfected mice with Acanthamoeba spp

From: Antioxidant defense in the eyes of immunocompetent and immunosuppressed mice infected with Acanthamoeba spp.

Parameter

C

CS

A

AS

SOD (U/mg protein)

 8 dpi

0.36 ± 0.14

0.37 ± 0.15

0.34 ± 0.16

0.36 ± 0.12

 16 dpi

0.36 ± 0.14

0.33 ± 0.08

 24 dpi

0.22 ± 0.09*

0.34 ± 0.06*

CAT (U/mg protein)

 8 dpi

7.96 ± 4.97*

7.46 ± 4.75

3.89 ± 2.26*

8.02 ± 3.74*

 16 dpi

2.36 ± 1.49*

11.36 ± 6.32*

 24 dpi

10.40 ± 3.43

6.68 ± 4.19

GPx (U/mg protein)

 8 dpi

4.62 ± 2.96

3.73 ± 1.87*

3.27 ± 1.75

1.31 ± 0.81*

 16 dpi

2.38 ± 1.02

3.19 ± 1.66

 24 dpi

2.36 ± 0.89

2.83 ± 1.07

GR (U/mg protein)

 8 dpi

3.77 ± 3.02*

2.46 ± 2.10

2.24 ± 1.69

0.98 ± 0.63

 16 dpi

0.75 ± 0.88*

1.43 ± 1.06

 24 dpi

2.15 ± 1.05

3.87 ± 3.72

GSH (mmol/mg protein)

 8 dpi

4.41 ± 1.29*

5.37 ± 2.12*

3.94 ± 0.89

4.23 ± 0.41

 16 dpi

3.58 ± 0.18*

6.57 ± 1.67*

 24 dpi

5.30 ± 1.02*

5.21 ± 0.98

  1. *Statistically significant difference (P < 0.05)
  2. Abbreviations: A, immunocompetent mice infected with Acanthamoeba spp.; AS, immunosuppressed mice infected with Acanthamoeba spp.; C, uninfected immunocompetent mice; CAT, catalase; CS, uninfected immunosuppressed; dpi, days post-Acanthamoeba spp. infection, GPx, glutathione peroxidase; GR, glutathione reductase; SOD, peroxide dismutase