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Table 5 Agreement rates between diagnostic tests results at the beginning and end of the sand fly season

From: Monitoring Leishmania infection and exposure to Phlebotomus perniciosus using minimal and non-invasive canine samples

Comparison

Sand fly season

Start

End

P-value

Kappa

95% CI

PA (%)

NA (%)

OA (%)

P-value

Kappa

95% CI

PA (%)

NA (%)

OA (%)

A vs B

0.002

0.671

0.501–0.842

70.0

98.8

94.2

0.016

0.747

0.605–0.888

77.6

97.0

94.7

A vs C

< 0.001

0.075

− 0.031–0.181

25.2

72.8

60.1

0.041

0.019

− 0.115–0.153

18.7

82.1

70.7

A vs Da

      

< 0.001

− 0.026

− 0.138–0.087

17.8

73.7

60.1

A vs E

< 0.001

0.014

− 0.059–0.009

21.9

53.6

41.2

< 0.001

0.002

− 0.041–0.045

24.2

24.9

24.5

A vs F

< 0.001

0.029

− 0.007–0.064

24.0

29.6

26.9

< 0.001

− 0.018

− 0.058–0.022

22.8

14.2

18.8

A vs G

< 0.001

0.037

− 0.014–0.088

24.3

41.7

34.1

< 0.001

0.008

− 0.030–0.046

35.3

24.6

23.6

B vs C

< 0.001

0.006

− 0.074–0.089

12.2

72.6

58.2

< 0.001

0.055

− 0.078–0.188

18.2

84.6

74.0

B vs Da

      

< 0.001

− 0.049

− 0.144–0.046

10.9

74.7

60.6

B vs E

< 0.001

0.021

− 0.031–0.073

14.0

55.0

40.9

< 0.001

− 0.001

− 0.038–0.035

17.2

24.8

21.2

B vs F

< 0.001

0.016

− 0.009–0.040

13.8

29.0

22.1

< 0.001

0.008

− 0.014–0.030

18.1

16.5

17.3

B vs G

< 0.001

0.008

− 0.032–0.047

13.0

40.5

29.3

< 0.001

0.018

− 0.007–0.043

18.8

23.4

21.2

C vs Da

      

0.007

0.002

− 0.132–0.132

27.1

71.1

58.7

C vs E

< 0.001

0.079

− 0.044–0.202

53.3

50.5

51.9

< 0.001

− 0.060

− 0.128–0.008

31.3

19.8

26.0

C vs F

< 0.001

0.015

− 0.072–0.103

55.6

26.8

44.7

< 0.001

− 0.013

− 0.060–0.034

34.8

14.4

26.0

C vs G

< 0.001

0.010

− 0.004–0.204

57.5

42.1

51.0

< 0.001

− 0.031

− 0.089–0.028

33.3

19.2

26.9

D vs Ea

      

< 0.001

0.022

− 0.051–0.095

50.4

25.3

40.4

D vs Fa

      

< 0.001

− 0.058

− 0.123–0.008

47.3

10.4

33.7

D vs Ga

      

< 0.001

− 0.031

− 0.104–0.041

48.0

18.5

36.5

E vs F

< 0.001

0.484

0.369–0.598

85.2

60.2

78.4

0.010

0.580

0.408–0.752

95.1

62.5

91.4

E vs G

< 0.001

0.542

0.425–0.660

85.2

68.2

79.8

0.540

0.505

0.334–0.677

93.3

54.1

88.5

F vs G

< 0.001

0.584

0.451–0.716

91.2

66.7

86.1

0.118

0.494

0.304–0.684

94.6

54.6

90.4

  1. aLeishmania DNA was not detected at the beginning of the phlebotomine sand fly season by conjunctival swab PCR
  2. Abbreviations: A, enzyme-linked immunosorbent assay; B, immunofluorescence antibody test; C, peripheral blood-polymerase chain reaction (PCR); D, conjunctival swab-PCR; E, 43 KDa yellow-related protein; F, 43 kDa yellow-related protein and 35.5 kDa apyrase; G, salivary gland homogenate; PA, positive agreement; NA, negative agreement; OA, overall agreement