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Table 1 Demographic and clinical characteristics of dogs infected with Babesia negevi n. sp. included in the study

From: A new piroplasmid species infecting dogs: morphological and molecular characterization and pathogeny of Babesia negevi n. sp.

Dog number

1

2

3

4

5

Sample ID

8726; 1001

4663

9835

0408

0651; 0544

Location

Meitar

Hashmonaim

Karmei Yosef

Ashkelon

Jerusalem

Year of diagnosis

2012

2012

2013

2012

2016

Sex; age (years)

F; 3

M; 4

F; 12.5

M; 3.5

M; 0.3

Breed

Mixed breed

Labrador Retriever

Mixed breed

Labrador Retriever

Mixed breed

Fever

41.2 °C

39.5 °C

38.9 °C

39.6 °C

39.0 °C

Lethargy

+

+

+

+

+

Anorexia

+

+

+

+

Pale mucous membranes

+

+

+

+

+

Icterus

+

+

+

Anemia; Hematocrit; MCV (fl); MCHC (g/l)

+; 0.34 l/l; 77.7; 305

+; 0.189 l/l; 66.7; 337

+; 0.17 l/l; 69.2; 353

+: 0.13 l/l; 84.6; 288

+; 0.084 l/l; 62.3; 272

Leukocytosis; WBC (× 109/l)

−; 11.80

−; 12.80

−; 9.13

+; 24.88

−; 6.45

Thrombocytopenia

+

+

+

+

Platelet count (× 109/l)

41

171

86

4

54

Co-infection

Borrelia persica infection noted on blood smear; PCR

+; +

+; +

+; +

−; −

+; +

Ehrlichia canis PCR

Hepatozoon canis PCR

+

Outcome

Survived

Died one day after treatment initiation

Survived

Died one day after treatment initiation

Survived

Treatment

Doxycycline and imidocarb dipropionate

Amoxicillin/ clavulanic acid; Imidocarb dipropionate

Amoxicillin; imidocarb dipropionate

Doxycycline; imidocarb dipropionate

Doxycycline; imidocarb dipropionate

  1. Notes: Hematocrit, reference interval (RI), 0.371–0.57 l/l; MCV (mean corpuscular volume) RI, 58.8–71.2 fl; MCHC (mean corpuscular hemoglobin concentration) RI, 310–362 g/l; WBC (white blood cell count) RI, 5.2–13.9 × 109/l; platelet count RI 143–400 × 109/l
  2. Abbreviations: F, female; M, male