Table 1 Demographic and clinical characteristics of dogs infected with Babesia negevi n. sp. included in the study
Dog number | 1 | 2 | 3 | 4 | 5 |
|---|---|---|---|---|---|
Sample ID | 8726; 1001 | 4663 | 9835 | 0408 | 0651; 0544 |
Location | Meitar | Hashmonaim | Karmei Yosef | Ashkelon | Jerusalem |
Year of diagnosis | 2012 | 2012 | 2013 | 2012 | 2016 |
Sex; age (years) | F; 3 | M; 4 | F; 12.5 | M; 3.5 | M; 0.3 |
Breed | Mixed breed | Labrador Retriever | Mixed breed | Labrador Retriever | Mixed breed |
Fever | 41.2 °C | 39.5 °C | 38.9 °C | 39.6 °C | 39.0 °C |
Lethargy | + | + | + | + | + |
Anorexia | + | + | + | + | − |
Pale mucous membranes | + | + | + | + | + |
Icterus | − | + | − | + | + |
Anemia; Hematocrit; MCV (fl); MCHC (g/l) | +; 0.34 l/l; 77.7; 305 | +; 0.189 l/l; 66.7; 337 | +; 0.17 l/l; 69.2; 353 | +: 0.13 l/l; 84.6; 288 | +; 0.084 l/l; 62.3; 272 |
Leukocytosis; WBC (× 109/l) | −; 11.80 | −; 12.80 | −; 9.13 | +; 24.88 | −; 6.45 |
Thrombocytopenia | + | – | + | + | + |
Platelet count (× 109/l) | 41 | 171 | 86 | 4 | 54 |
Co-infection | |||||
Borrelia persica infection noted on blood smear; PCR | +; + | +; + | +; + | −; − | +; + |
Ehrlichia canis PCR | − | − | − | − | − |
Hepatozoon canis PCR | + | − | − | − | − |
Outcome | Survived | Died one day after treatment initiation | Survived | Died one day after treatment initiation | Survived |
Treatment | Doxycycline and imidocarb dipropionate | Amoxicillin/ clavulanic acid; Imidocarb dipropionate | Amoxicillin; imidocarb dipropionate | Doxycycline; imidocarb dipropionate | Doxycycline; imidocarb dipropionate |