Assessing cross-resistance within the pyrethroids in terms of their interactions with key cytochrome P450 enzymes and resistance in vector populations

Table 2. Correlations between resistance to different pyrethroids in African malaria vector species.

Pyrethroid combination	Paired sample size (N)	r
Deltamethrin vs λ-cyhalothrin
Anopheles funestus subgroup	46	0.818*
Anopheles funestus	24	0.865*
Anopheles arabiensis	28	0.946*
Anopheles coluzzii	18	0.863*
Anopheles coluzzii/gambiae^a	19	0.603*
Anopheles gambiae	19	0.418 n.s.
Permethrin vs λ-cyhalothrin
Anopheles funestus subgroup	26	0.786*
Anopheles funestus	16	0.845*
Anopheles arabiensis	31	0.859*
Anopheles coluzzii	14	0.740*
Anopheles coluzzii/gambiae^a	17	0.790*
Anopheles gambiae	4	Not tested
Deltamethrin vs permethrin
Anopheles funestus subgroup	113	0.608*
Anopheles funestus	69	0.726*
Anopheles arabiensis	116	0.840*
Anopheles coluzzii	48	0.793*
Anopheles coluzzii/gambiae^a	63	0.714*
Anopheles gambiae	75	0.782*

n.s., non-significant results (at the 0.05 level with a Holm-Bonferroni correction)
*Significant results (at the 0.05 level with a Holm-Bonferroni correction)
^aAnopheles coluzzii/gambiae refers to mosquito samples that were undifferentiated between An. coluzzii (M form) and An. gambiae (S form), before they were recognised as two species

ISSN: 1756-3305