Table 2 Flea count data for each treatment group and statistical analysis of flea count reduction from baseline for each treatment group
Flea count data | Lotilaner treatment group | Fipronil and S-methoprene treatment group |
|---|---|---|
Day 0 (pre-treatment) | ||
Arithmetic mean ± SD | 46.3 ± 61.0 | 45.3 ± 59.5 |
Rangea | 5–251 | 5–251 |
Geometric mean | 24.6 | 25.8 |
Day 30 | ||
Arithmetic mean ± SD | 1.3 ± 5.1 | 27.3 ± 52.0 |
Range | 0–48 | 0–251 |
Geometric mean | 0.4 | 9.9 |
% Efficacyb | 98.3 | 61.6 |
Statistical analysis | t(114) = 29.05, P < 0.0001 | t(61) = 6.86, P < 0.0001 |
Day 60 | ||
Arithmetic mean ± SD | 0.0 ± 0.2 | 17.6 ± 36.0 |
Range | 0–1 | 0–184 |
Geometric mean | 0.0 | 6.3 |
% Efficacyb | 99.9 | 75.4 |
Statistical analysis | t(203) = 32.65, P < 0.0001 | t(59) = 8.86, P < 0.0001 |
Day 90 | ||
Arithmetic mean ± SD | 0.1 ± 0.6 | 9.0 ± 12.0 |
Range | 0–6 | 0–59 |
Geometric mean | 0.0 | 4.0 |
% Efficacyb | 99.9 | 84.7 |
Statistical analysis | t(221) = 32.94, P < 0.0001 | t(51) = 9.63, P < 0.0001 |