Deworming women of reproductive age during adolescence and pregnancy: what is the impact on morbidity from soil-transmitted helminths infection?

Table 3 Average prevalences of moderate- and high-intensity infections infections in women of reproductive age

Model^a	Age period (years)	SB only, mean (95% credible interval)	SB + WRA, mean (95% credible interval)	% Reduction, mean (95% credible interval)^b	P value
ICL	15–50	3.42 × 10⁻⁴ (0–1.43 × 10⁻³)	5.23 × 10⁻⁵ (0–4.75 × 10⁻⁴)	41 (0–100)	9.33 × 10⁻⁷
ICL	15–19	1.97 × 10⁻³ (0–0.01)	3.33 × 10⁻⁴ (0–3.33 × 10⁻³)	37 (0–100)	1.27 × 10⁻⁶
ICL	20–50	0 (0–0)	0 (0–0)	0 (0–0)	NA
EMC	15–50	4.56 (4.11–4.97)	3.51 (3.13–3.85)	23.0 (20.5–25.7)	< 2.2 × 10⁻¹⁶
EMC	15–19	3.72 (3.29–4.11)	1.75 (1.50–2.01)	53.0 (48.0–58.6)	< 2.2 × 10⁻¹⁶
EMC	20–50	4.70 (4.25–5.10)	3.81 (3.41–4.17)	19.0 (16.2–21.9)	< 2.2 × 10⁻¹⁶

Values in table are presented as the mean prevalence (%)
^aModerate baseline prevalence (20–50%), semi-annual SB treatment. The FoI inputted into the cohort model was extracted from ICL and EMC fully stochastic individual-based models with ongoing semi-annual SB treatment, i.e. FoI decreased over time. In the ICL model prevalences of M&HI infections in WRA are below 1%. Therefore, the reduction in the prevalence of M&HI infections in absolute numbers is negligible and the uncertainty large
^bThe relative reduction is only calculated from time points where the prevalence of M&HI infections in simulations with the old treatment strategy (SB only) is > 0. All time points were used in the statistical comparison

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