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Table 1 Structures of oxadiazole-2-oxide derivatives and their inhibitory activity against the TrxR activity of SWAP containing wtSjTGR and rSjTGR-Sec

From: Synthesis of oxadiazole-2-oxide derivatives as potential drug candidates for schistosomiasis targeting SjTGR

  1. IC50 values > 50 μM signify lack of fitted curve through the dose-response data—that is, flat response within the range tested
  2. NA not applicable