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Table 6 Occurrence of pathological changes in tissues of pups from group B and control group PU on 14th day postpartum.

From: Impact of Babesia microti infection on the initiation and course of pregnancy in BALB/c mice

Organ

Type of pathological changes

group B (n = 18)

Control group PU (n = 12)

Statistical values

Spleen

Extramedullary haematopoiesis

93% (13/14)

91% (10/11)

NS

Lymphoid hyperplasia

57% (8/14)

91% (10/11)

NS

Liver

Inflammation

100% (18/18)

100% (12/12)

NS

Congestion

83% (15/18)

50% (6/12)

NS

Degeneration of the hepatocytes

6% (1/18)

8% (1/12)

NS

Extramedullary haematopoiesis

50% (9/18)

42% (5/12)

NS

Kidneys

Necrosis of rental tubules epithelium

100% (18/18)

92% (11/12)

NS

Congestion

61% (11/18)

50% (6/12)

NS

Brain

Cerebral oedema

94% (17/18)

100% (12/12)

NS

Neuronophagia

6% (1/18)

25% (3/12)

NS

Nerve cell (neuron) necrosis

28% (5/18)

42% (5/12)

NS

Hyperaemia

22% (4/18)

17% (2/12)

NS

Heart

Necrosis of cardiomyocytes

44% (8/18)

83% (10/12)

χ2 = 4.84, df = 1, p <  0.05

Inflammation of the heart muscle

61% (11/18)

67% (8/12)

NS

Atrophy of cardiac myocytes

28% (5/18)

8% (1/12)

NS

Congestion of the heart muscle

22% (4/18)

42% (5/12)

NS

Lungs

Atelectasis

100% (17/17)

91% (10/11)

NS

Pneumonitis, interstitial inflammation

88% (15/17)

91% (10/11)

NS

Emphysema

29% (5/17)

18% (2/11)

NS

Congestion

47% (8/17)

45% (5/11)

NS

Siderophages

6% (1/17)

0% (0/11)

NS