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Table 3 Summary of adult flea counts, percent efficacy and comparison results

From: Efficacy of lotilaner (Credelio™) against experimentally induced infestations of the adult cat flea, Ctenocephalides felis, and flea eggs following oral administration to cats

Day

Intent-to-treat population

Number of cats flea free

Arithmetic mean (%efficacy)

Comparison

Control (N = 10)

Lotilaner (N = 10)

Control (N = 10)

Lotilaner (N = 10)

1

0

0

89.7

0.0 (100)

t(9) = 181.07, P < 0.0001a

Z = 4.04, P < 0.0001a

7

1

10

88.5

0.0 (100)

t(9) = 165.98, P < 0.0001a

Z = 4.04, P < 0.0001a

14

1

10

90.6

0.1 (99.9)

t(9) = 62.04, P < 0.0001a

Z = 3.97, P < 0.0001a

21

1

9

84.3

0.1 (99.9)

t(9) = 62.04, P < 0.0001a

Z = 3.97, P < 0.0001a

30

0

9

86.5

0.2 (99.8)

t(9) = 37.55, P < 0.0001a

Z = 3.97, P < 0.0001a

  1. Comparison results of both the parametric and non-parametric tests are presented
  2. aValues significantly decreased in comparison to the control group