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Fig. 5 | Parasites & Vectors

Fig. 5

From: The NF-κB signalling pathway and TM7SF3 contribute to liver fibrosis caused by secreted phospholipase A2 of Clonorchis sinensis

Fig. 5

TM7SF3 antibody inhibited the activation of HSCs incubated with MBP-CssPLA2 by blocking TM7SF3. The mRNA levels of collagen I and collagen III in the group of LX-2 cells incubated with 25 μg/ml MBP-CssPLA2 + anti-TM7SF3 antibody were lower than those in the group of cells incubated with 25 μg/ml MBP-CssPLA2. a Measurement of collagen I mRNA levels in HSCs treated with an anti-TM7SF3 antibody (t(4) = 12.81, P = 0.0002). b Measurement of collagen III mRNA levels in HSCs treated with an anti-TM7SF3 antibody (t(4) = 6.245, P = 0.0034)

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Parasites & Vectors

ISSN: 1756-3305

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