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Table 4 Proteases differentially upregulated 7 days after feeding (7 vs 0)

From: RNA-seq analysis and gene expression dynamics in the salivary glands of the argasid tick Ornithodoros erraticus along the trophogonic cycle

Description Accession No. transcripts RPKM 0 RPKM 7 Log2FC
Metalloproteases
 A disintegrin and metalloproteinase with thrombospondin motifs 8 (ADAMs) KFM57926 1 10.98 24.49 1.16
 Carboxypeptidase Q AMO02552 1 12.20 40.37 1.73
 Endothelin converting enzyme KZC14076, XP_022117928, B7QLL2, B7PLU3 6 79.37 205.27 1.04–1.93
 Hypothetical protein B7P43_G04849 PNF39037 1 3.64 10.07 1.46
 Hypothetical protein DAPPUDRAFT_187662 EFX85417 2 4.50 11.38 1.31–1.36
 Hypothetical protein Phum_PHUM474680 EEB17615 2 2.97 12.91 2.11–2.14
 Hypothetical protein TSAR_002326 OXU27510.1 1 6.08 25.88 2.09
 Membrane metallo-endopeptidase ODM96912, XP_015911874, KFM79078 3 18.65 66.46 1.58–2.23
 Metalloprotease BAE00066, ABI52776, BAF43575, ABI52714, ABI52747, ABI52815, ABI52719, BAE72661, ABI52779, ABI52738, BAE72664, ABI52662, ABI52652, B7Q2B8, B7PPE9, B7Q2C1, B7Q4I3, DAA34338 125 4024.53 14,474.84 1.08–3.24
 Metalloprotease 1 AIE44747, AIE44750, AIE44753 4 103.52 277.06 1.04–1.59
 Metalloprotease 2 AIE44748 1 26.01 57.17 1.14
 Metalloprotease 4 AIE44755 7 127.35 290.99 1.07–1.61
 Metis1 protein CAO00625 14 204.99 574.06 1.09–2.25
 Metis2 protein CAO00626 4 21.61 61.89 1.32–1.61
 Metis3 protein CAO00627 32 494.29 1,754.92 1.00–2.41
 Metis4 protein CAO00628 9 335.26 1,281.06 1.08–2.61
 Metis5 protein CAO00629 1 14.89 86.24 2.53
 M20 domain-containing peptidase B7P153 3 4.84 11.43 1.14–1.24
 Neprilysin XP_001849326, ISCW024547-PA, B7QAF9, B7Q3V5, B7PL32, AAL91975, DAA34245 14 868.32 2,009.44 1.03–2.49
 Neprilysin-1 XP_019696599, XP_022255642 9 88.88 340.64 1.12–2.55
 Neprilysin-2 XP_015795185, XP_026818640, XP_008476829, XP_023343136, XP_019868485 9 294.8 845.97 1.17–2.06
 Neprilysin-4 XP_024228249, XP_026469709 2 40.41 126.42 1.63–1.65
 Neprilysin-11 RWS07493, XP_001600059 4 39.64 89.24 1.00–1.44
 Peptidase M12B domain-containing protein B7QM92 15 518.28 2,083.55 1.03–3.55
 Peptidase-like protein ADF28505 1 17.18 55.67 1.70
 Salivary gland metalloprotease AAZ39657, AAZ39658, AAZ39659
EEC19961, EEC18166, DAA34140, DAA34198
20 268.52 791.84 1.16–1.84
 Secreted metalloprotease B7Q2C0, B7QM91, AAM93653 7 77.82 335.34 1.39–2.98
 Truncated metalloprotease ABR23495 7 199.09 635.98 1.09–2.05
 Venom metalloproteinase 3-like XP_008547408, XP_014223136 2 21.04 75.98 1.85–1.86
 Venom metalloproteinase antarease-like TtrivMP_A XP_018494555, XP_022665601 3 35.09 128.99 1.30–1.90
 Zinc-dependent metalloprotease ACB70344 28 159.78 572.61 1.00–3.37
Serine proteases
 Carboxypeptidases B7QF76 14 149.98 383.33 1.28–1.47
 Lysosomal protective protein XP_013784602 3 9.64 28.98 1.47–1.77
 Retinoid-inducible serine carboxypeptidase XP_015927829, KFM77940, XP_013787581 11 46.45 234.46 1.78–2.73
 Scpep1 PRD34546 2 269.79 1,921.7 2.82–2.84
 Serine carboxypeptidases B7PJ32, B7PJ51, DAA34155, 14 538.04 4,083.83 2.87–3.09
 Serine protease K12H4.7 XP_003742341 1 2.03 18.12 3.15
 Venom serine carboxypeptidase XP_017788931, XP_026806100 2 6.68 75.55 3.15–3.60
Cysteine proteases
 Midgut cysteine proteinase 4 AAO60047 1 8.17 17.33 1.08
  1. For each protein description, the accession codes and number of transcripts assigned, the average expression level in RPKM for unfed (RPKM 0) and 7 days fed (RPMK 7) females, and the range of log2FC reached are provided
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