Fig. 1

The candidate fungal extract blocks P. falciparum transmission through feeding or spraying. a The fungal extract (GFEL-12E6) significantly inhibited P. falciparum infection in mosquito midguts in the SMFA. The experiment was independently conducted three times and the results were consistent. b Exposure to the fungal extract significantly inhibited P. falciparum infection in mosquito midguts. The fungal extract in acetone was sprayed onto cups and dried. Mosquitoes were placed in the cup for 24 h before the SMFA. This showed one experiment, and the experiment was independently conducted three times, and the results were consistent. The red line indicates the median number of oocysts in mosquitoes in each treatment. The bold lines at zero oocysts indicate many mosquitoes with zero oocysts. N: the number of mosquitoes in the group. Infection (%): the percentage of infected mosquitoes. Median: the median number of oocysts in mosquito midguts