Fig. 5
From: A novel fungal metabolite inhibits Plasmodium falciparum transmission and infection
Pulixin was able to inhibit the development of the asexual-stage P. falciparum in blood. The test for each concentration was replicated three times and the assays were repeated. The profiles show the means and standard errors. a Parasitemia at days 1, 2, 3, and 4 after inoculation with P. falciparum-infected blood without pulixin. Significantly more (p < 0.001) parasite-infected cells at day 4 comparing to day 1. b Parasitemia on day 4 after incubation with different concentrations of pulixin. Significantly fewer P. falciparum-infected cells were observed when the concentration of pulixin was greater than 0.01 μg/mL (p < 0.05), compared to the control (0 μg/mL pulixin)