Skip to main content
Fig. 1 | Parasites & Vectors

Fig. 1

From: Vaccination against the brown stomach worm, Teladorsagia circumcincta, followed by parasite challenge, induces inconsistent modifications in gut microbiota composition of lambs

Fig. 1

a Experimental design. Two studies aimed to investigate the impact of vaccination against, and experimental infection with, Teladorsagia circumcincta (Tc) were conducted in 2017 (17) and 2018 (18), respectively. In each experiment, three groups of lambs (I to III) were enrolled and subjected to (I) inoculation of a recombinant vaccine against T. circumcincta followed by experimental infection (Vac/Tc+_17 and Vac/Tc+_18, respectively); (II) experimental infection with or without prior inoculation of vaccine adjuvant (Adj/Tc+_17 and Tc+_18, respectively), while lambs in groups III were left unvaccinated and uninfected (Tc−_17 and Tc−_18, respectively). Faecal samples were collected at designated time points for DNA extraction and high-throughput sequencing of the bacterial 16S rRNA gene. *Samples for Tc−_17 were unavailable. b Number of faecal samples subjected to metagenomics sequencing, according to trial, animal group and time point

Back to article page