Treatment | Dosage | Days of treatment | Number of infected dogs a | Adult D. immitis worm counts | Efficacy compared to negative control c | |
---|---|---|---|---|---|---|
Individual worm counts | Geometric mean b | Percentage reduction | ||||
Negative control | NA | 0 | 6 of 6 | 23, 25, 29, 33, 35, 37 | 29.9g | NA |
ProHeart 12 | 0.5 mg/kg moxidectin d | 0 | 0 of 5 | 0 | 0h | 100 |
Heartgard Plus | Min. of 6 µg/kg ivermectin e | 0, 30, 60, 90, 120, 150 | 6 of 6 | 19, 21, 24, 33, 34, 34 | 26.8g | 10.5 |
Interceptor Plus | Min. of 0.5 mg/kg milbemycin oxime f | 0, 30, 60, 90, 120, 150 | 6 of 6 | 13, 24, 27, 30, 31, 35 | 25.5g | 14.6 |