Treatment | Dosage | Days of treatment | Number of infected dogsa | Adult D. immitis worm counts | Efficacy compared to negative control c | |
---|---|---|---|---|---|---|
Individual worm counts | Geometric meanb | Percentage reduction | ||||
Negative control | NA | 0 | 6 of 6 | 27, 32, 34, 36, 37, 46 | 34.9g | NA |
ProHeart 12 | 0.5 mg/kg moxidectin d | 0 | 4 of 6 | 0, 0, 1, 1, 1, 1 | 0.6h | 98.3 |
Heartgard Plus | Min. of 6 µg/kg ivermectine | 0, 30, 60, 90, 120, 150, 180, 210, 240, 270, 300, 330 | 6 of 6 | 12, 20, 23, 24, 27, 29 | 21.7i | 37.7 |
Interceptor Plus | Min. of 0.5 mg/kg milbemycin oximef | 0, 30, 60, 90, 120, 150, 180, 210, 240, 270, 300, 330 | 6 of 6 | 14, 19, 23, 24, 25, 37 | 22.7i | 34.9 |