Serum amyloid A levels and alpha 2 and gamma globulins on serum protein electrophoresis in cats exposed to and infected with Leishmania infantum

Table 1 Number of sampled cats, and serum protein electrophoresis and serum amyloid A results

Variable	GROUP 1 Healthy control	GROUP 2 Neoplastic or inflammatory conditions	GROUP 3 Leishmania infantum seropositive, qPCR-negative	GROUP 4 L. infantum seropositive, qPCR positive
Total number of samples analysed	16 (15 for SPE)	20	20	12 (11 for SAA)
SAA results (mg/l)^a	0.00 (0.00–0.00)	0.85 (0.00–49.55)	0.00 (0.00–4.53)	0.00 (0.00–7.5)
SPE results^b
Alpha 2 globulins increased	3 (20.0 ± 10.3)	16 (80.0 ± 8.9)	14 (70.0 ± 10.2)	9 (75.0 ± 12.5)
Gamma globulins increased	0 (0 ± 0)	13 (65.0 ± 10.7)	10 (50.0 ± 11.2)	7 (58.3 ± 14.2)

qPCR Quantitative (real-time) PCR, SAA serum amyloid A, SPE serum protein electrophoresis
Reference ranges: SAA (mg/l): < 0.5; alpha 2 globulins (g/l) [27]: 2.94–10.25; gamma globulins (g/l) [27]): 4.33–21.40
^aData presented as median (interquartile range)
^bData presented as a number (percentage ± standard error on the percentage [SEP])

ISSN: 1756-3305