Fig. 8
Protein–protein interaction network analysis. a The network consists of 77 DEPs identified between the acutely infected and normal mouse groups. The red node indicates upregulated and the green node indicates downregulated proteins (log2 fold change). The node size indicates high interaction degree (large) or low degree (small). Proteins that are associated to each other are linked by an edge. The color of the edge indicates the combined interaction score for a particular protein pair. b Validation of DEPs by PRM analysis