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Table 4 Dogs positive for heartworm antigen (Ag) or antibody (Ab) in context of their microfilariae (Mf) status

From: Optimizing heartworm diagnosis in dogs using multiple test combinations

Mf results

POCa Ag POS

DiroCHEK® Ag POS

DiroCHEK® Ag + HT POS

Ab POSb

All Mf NEG (n = 82)

2 (2.4%)

3 (3.7%)

10 (12.2%)

20 (24.4%)

Di Mf NEG (n = 87)

3 (3.4%)

5 (5.7%)

15 (17.2%)

22 (25.3%)

Any Mf POS (n = 18)

12(66.6%)

13 (72.2%)

18 (100%)

13 (72.2%)

Di Mf POS (n = 13)

11 (84.6%)

11 (84.6%)

13 (100%)

11 (84.6%)

Dr Mf POS (n = 1)

0 (0%)

0 (0%)

1 (100%)

1 (100%)

Ar Mf POS (n = 4)

1 (25%)

2 (50%)

4 (100%)

1 (25%)

  1. POS, positive; NEG, negative; Ag, antigen; POC, point of care test: Witness and IDEXX SNAP were performed with 100% agreement; POS, positive; HT, heat treatment; Di, Dirofilaria immitis; Dr, D. repens; Ar, Acanthocheilonema reconditum
  2. aWitness® and IDEXX SNAP® were performed with 100% agreement
  3. bHeska and Antech Ab results were combined; these tests are not validated for use in dogs