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Fig. 2 | Parasites & Vectors

Fig. 2

From: Transcriptomic profiling of three-dimensional cholangiocyte spheroids long term exposed to repetitive Clonorchis sinensis excretory-secretory products

Fig. 2

Transcriptomic dynamics by ESP treatment in H69 spheroids. Common gene expression patterns through two independent experiments and one experiment were identified by the microarray and RNA-Seq platforms a and b, respectively. Principal component analysis (PCA) of microarray (a) and RNA-Seq (b) analysis. The values indicate the amount of variation attributed to each principal component. Small blue circles indicate individual samples, red asterisks indicate the average between experimental replicates, and larger yellow ovals represent each experimental group. c, d Volcano plot of microarray of ESP-exposed H69 spheroids for 5 days (c) and 10 days (d) illustrating genes from the filtered data set that are significant DEGs between untreated- and ESP-treated H69 spheroids. Blues are significantly regulated but at less than twofold change, greens have greater than twofold change, but this is not significant, while reds are significant by more than twofold

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