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Fig. 3 | Parasites & Vectors

Fig. 3

From: Serum proteomic profiling in patients with advanced Schistosoma japonicum-induced hepatic fibrosis

Fig. 3

Bioinformatics analysis of differentially expressed proteins in serum samples from healthy controls vs those from patients with SHF-F2. a Volcano plot representing the changes in protein abundance (groups B [SHF-F2 patients] vs A [healthy controls]). A total of 66 dysregulated proteins with a fold change of ≥ ±  1.5 and P values < 0.05 were identified. b Hierarchical clustering of the 66 dysregulated proteins (groups B vs A). c Gene ontology (GO) analysis of 66 dysregulated proteins (groups B vs A). The abscissa repressents enriched GO function classifications, which are divided into three major categories: biological process (BP), molecular function (MF) and cellular component (CC). d Analysis of Eukaryotic Orthologous Groups (KOG) of 66 dysregulated proteins (group B vs group A)

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