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Fig. 1 | Parasites & Vectors

Fig. 1

From: Involvement of TLR4 signaling regulated-COX2/PGE2 axis in liver fibrosis induced by Schistosoma japonicum infection

Fig. 1

The components of the COX2/PGE2 axis are overexpressed in the livers of mice with 8-week Sj infections. C57BL/6 mice were infected with 20 ± 3 cercariae of Sj for 0 or 8 weeks. Mice liver samples were kept in TRIzol or in RIPA for RNA or total protein extraction respectively. a The relative RNA expression level of COX2, Ptges, Ptger1-4, Abcc4, and Slco2a1 in indicated mice liver were measured using RT-qPCR. Gapdh acts as an internal control (t test, *p < 0.05, ****P < 0.0001). b The protein expression level of COX2, mPGES-1, and EP1-4 in mice liver homogenates were detected by western blotting. GAPDH is used as a loading control. Data are presented as mean ± SEM from 5 to 9 mice per group

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