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Table 5 Frequency of clinical signs according to the result of IHC for the detection of Leishmania spp. amastigote forms in 143 dogs from the town of Barra Mansa, Rio de Janeiro, Brazil (2012 to 2013)

From: Frequency of detection and load of amastigotes in the pancreas of Leishmania infantum-seropositive dogs: clinical signs and histological changes

Clinical signs

IHC for detection of Leishmania amastigotes

p value

Negative (N = 121)

Positive (N = 22)

n

%

95% CI (%)

n

%

95% CI (%)

Poor body condition/cachexia

21

17.4

11.1–0.2

9

40.9

20.7–63.6

0.021a

Skin changes

33

27.3

19.6–36.1

7

31.8

13.9–54.9

0.797

Hepato-/splenomegaly

34

28.1

20.3–37.0

6

27.3

10.7–50.2

1.000

Lymphadenomegaly

18

14.9

9.1–22.5

5

22.7

7.8–45.4

0.353

Keratoconjunctivitis

14

11.6

6.5–18.6

4

18.2

5.2–40.3

0.482

Diarrhea

7

5.8

2.3–11.6

2

9.1

1.1–29.2

0.629

Anorexia

4

3.3

0.9–8.2

1

4.5

0.1–22.8

0.572

Vomiting

3

2.5

0.5–7.1

0

0.0

0.0–15.5

_b

Absence of clinical signs

50

41.3

32.4–50.6

8

36.4

17.2–59.3

0.814

  1. N number of dogs, n number of samples, IHC immunohistochemistry, 95% CI 95% confidence interval
  2. aStatistically significant difference at the 5% level
  3. bStatistical analysis was not possible because of the absence of vomiting in one of the groups