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Table 2 Results of non-inferiority statistical analysis of the performance of Panda® Net and Yahe® LN nets versus standard reference PermaNet® 2.0

From: Evaluation of Yahe® and Panda® 2.0 long-lasting insecticidal nets against wild pyrethroid-resistant Anopheles gambiae s.l. from Côte d’Ivoire: an experimental hut trial

Outcomes

Treatment arms

PermaNet® 2.0, unwashed

Mean: 25.9 (19.7–33.4)

PermaNet® 2.0, washed 20 times

Mean: 51.2 (43.5–58.8)

Blood feeding

PermaNet® 2.0, unwashed

Mean: 25.9 (19.7–33.4)a

OR = 1

OR = 0.33 (0.26–0.43)

PermaNet® 2.0, washed 20 times

Mean: 51.2 (43.5–58.8)c

OR = 2.99 (2.34–3.82)

OR = 1

Panda® Net 2.0, unwashed

Mean: 19.7 (13.6–27.7)a

OR = 0.70 (0.47–1.04)

OR = 0.23 (0.16–0.33)

Panda® Net 2.0, washed 20 times

Mean: 25.3 (19.2–32.5)a

OR = 0.97 (0.72–1.30)

OR = 0.32 (0.25–0.41)

Yahe® LN, unwashed

Mean: 39.5 (31.5–48.0)b

OR = 1.86 (1.39–2.49)

OR = 0.62 (0.49–0.79)

Yahe® LN washed 20 times

Mean: 53.9 (45.9–61.6)c

OR = 3.33 (2.58–4.30)

OR = 1.11 (0.93–1.33)

Total mortality

PermaNet® 2.0, unwashed

Mean: 23.0 (18.0–28.8)b

OR = 1

OR = 2.73 (2.04–3.67)

PermaNet® 2.0, washed 20 times

Mean: 9.8 (7.6–12.6)a

OR = 0.37 (0.27–0.49)

OR = 1

Panda® Net 2.0, unwashed

Mean: 53.7 (44.9–62.2)c

OR = 3.89 (2.71–5.58)

OR = 10.65 (7.54–15.04)

Panda® Net 2.0, washed 20 times

Mean: 25.3 (20.2–31.2)b

OR = 1.14 (0.85–1.53)

OR = 3.11 (2.37–4.09)

Yahe® LN unwashed

Mean: 14.5 (10.7–19.2)a

OR = 0.57 (0.40–0.80)

OR = 1.55 (1.11–2.17)

Yahe® LN, washed 20 times

Mean: 10.6 (8.1–13.9)a

OR = 0.40 (0.30–0.54)

OR = 1.09 (0.82–1.45)

  1. Bold values indicate non inferiority criterion
  2. Non-inferiority of Panda® Net 2.0 and Yahe® LN combined feeding inhibition and 24 h mortality with PermaNet® 2.0 as the reference. The candidate net is deemed non-inferior if (i) the upper 95% CI estimate of the odds ratio (OR) describing the difference in mosquito blood feeding between the candidate net and PermaNet 2.0 is greater than 1.43; (ii) the lower 95% CI estimate of the OR describing the difference in mosquito mortality between the candidate net and PermaNet 2.0 is greater than 0.7
  3. Outcome values (mean) in the same column sharing the same letter superscript do not differ significantly at a 5% level (GLM, p > 0.05)