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Table 4 Significant signals from DESeq2 testing of association between Blastocystis positivity and individual taxa within the stool bacteriome

From: Blastocystis in the faeces of children from six distant countries: prevalence, quantity, subtypes and the relation to the gut bacteriome

Phylum Class Order Family Genus Mean abundance of genus Fold-diff (genus) Corrected adjusted p value
Actinobacteria Actinobacteria Bifidobacteriales Bifidobacteriaceae ↓ Bifidobacterium 6.0% 0.36 6.2 × 10–6
Firmicutes Negativicutes Selenomonadales Veillonellaceae ↓ Veillonella 1.3% 0.22 3.0 × 10–4
Bacilli Lactobacillales Streptococcaceae ↓ Streptococcus 1.5% 0.28 9.4 × 10–7
Lactobacillaceae ↓ Lactobacillus 1.3% 0.39 7.7 × 10–3
Clostridia Clostridiales Lachnospiraceae ↓ Fusicatenibacter 1.6% 0.45 1.0 × 10–3
↓ Blautia 7.9% 0.42 8.9 × 10–8
↓ Anaerostipes 1.6% 0.38 6.2 × 10–6
Ruminococcaceae ↓ Subdoligranulum 2.3% 0.48 7.9 × 10–4
↑ Ruminococcaceae UCG-002 1.5% 2.65 8.1 × 10–5
↑ Ruminococcaceae UCG-014 1.6% 4.16 7.7 × 10–4
  1. All models were adjusted for nationality; PCR positivity for Blastocystis was a dichotomous predictor
  2. The model predictors were nationality and Blastocystis positivity in real-time PCR. The fold difference is the coefficient for the particular genus, associated with Blastocystis positivity. The P value comes from this adjusted DESeq2 model and is corrected for the number of tested taxa. Shown are significantly associated taxa with a mean abundance > 1%
  3. Arrows and bold typeface indicate statistically significant associations