Fig. 6
From: In vivo and in vitro efficacy of crocin against Echinococcus multilocularis
a–d In vivo activity of crocin against E. multilocularis metacestodes. Fourteen weeks after infection of BALB/c mice with protoscoleces, the mice were administered crocin intragastrically for 6 weeks. The positive control treatment was 100 mg/kg albendazole (ABZ). a Gross morphology of metacestodes. b Quantitative weight analysis of the metacestode masses. The data are presented as the mean ± SD. c E. multilocularis metacestodes were observed by HE staining. Protoscoleces were still observed in the control and ABZ groups. Scale bar = 200 μm. FT Fibrous tissue, Va vacuole. d LL PAS staining. The sections show PAS-positive LLs of E. multilocularis metacestodes. Scale bar = 200 μm. For other abbreviations, see Figs. 1 and 3