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Table 1 Blood cell indexes and serum biochemical indexes of BALB/c mice after 6 weeks of crocin treatment (n = 6)

From: In vivo and in vitro efficacy of crocin against Echinococcus multilocularis

BALB/c mice

Control

Crocin50

Crocin100

F

P

ALT (U/L)

62.17 ± 5.71

62.17 ± 3.19

65.50 ± 4.93

0.9945

0.3930

AST (U/L)

189.80 ± 25.90

186.30 ± 2.62

185.00 ± 22.26

0.0668

0.9356

TBIL (μmol/L)

0.66 ± 0.21

0.60 ± 0.10

0.59 ± 0.16

0.2914

0.7513

DBIL (μmol/L)

0.09 ± 0.04

0.13 ± 0.05

0.13 ± 0.04

1.7910

0.2008

IBIL (μmol/L)

0.55 ± 0.18

0.53 ± 0.15

0.60 ± 0.21

0.2591

0.7752

TP (g/L)

61.93 ± 2.23

62.30 ± 3.30

61.22 ± 3.21

0.2090

0.8137

ALB (g/L)

28.02 ± 1.95

29.08 ± 2.03

28.58 ± 1.66

0.4805

0.6277

ALP (U/L)

84.50 ± 4.64

83.67 ± 6.15

86.33 ± 8.02

0.2710

0.7663

CRE (μmol/L)

15.80 ± 3.06

16.03 ± 1.94

16.00 ± 2.97

0.0131

0.9870

BUN (mmol/L)

9.24 ± 0.95

7.11 ± 1.81*

7.30 ± 0.55*

5.5770

0.0155

White blood cells (× 109/L)

8.14 ± 1.40

8.10 ± 0.99

8.08 ± 1.22

0.0040

0.9962

Haemoglobin (g/L)

129.30 ± 8.07

128.80 ± 9.50

129.30 ± 11.98

0.0050

0.9950

Platelets (× 109/L)

466.20 ± 45.31

481.80 ± 64.36

466.80 ± 63.64

0.1379

0.8723

  1. Crocin50 Crocin administered at 50 mg/kg, Crocin100 crocin administered at 100 mg/kg, ALT alanine aminotransferase, AST aspartate aminotransferase, TBIL total bilirubin, DBIL direct bilirubin, IBIL indirect bilirubin, TP total protein,ALB albumin, ALP alkaline phosphatase, CRE creatinine, BUN blood urea nitrogen
  2. * P < 0.05 versus control