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Table 1 Blood cell indexes and serum biochemical indexes of BALB/c mice after 6 weeks of crocin treatment (n = 6)

From: In vivo and in vitro efficacy of crocin against Echinococcus multilocularis

BALB/c mice Control Crocin50 Crocin100 F P
ALT (U/L) 62.17 ± 5.71 62.17 ± 3.19 65.50 ± 4.93 0.9945 0.3930
AST (U/L) 189.80 ± 25.90 186.30 ± 2.62 185.00 ± 22.26 0.0668 0.9356
TBIL (μmol/L) 0.66 ± 0.21 0.60 ± 0.10 0.59 ± 0.16 0.2914 0.7513
DBIL (μmol/L) 0.09 ± 0.04 0.13 ± 0.05 0.13 ± 0.04 1.7910 0.2008
IBIL (μmol/L) 0.55 ± 0.18 0.53 ± 0.15 0.60 ± 0.21 0.2591 0.7752
TP (g/L) 61.93 ± 2.23 62.30 ± 3.30 61.22 ± 3.21 0.2090 0.8137
ALB (g/L) 28.02 ± 1.95 29.08 ± 2.03 28.58 ± 1.66 0.4805 0.6277
ALP (U/L) 84.50 ± 4.64 83.67 ± 6.15 86.33 ± 8.02 0.2710 0.7663
CRE (μmol/L) 15.80 ± 3.06 16.03 ± 1.94 16.00 ± 2.97 0.0131 0.9870
BUN (mmol/L) 9.24 ± 0.95 7.11 ± 1.81* 7.30 ± 0.55* 5.5770 0.0155
White blood cells (× 109/L) 8.14 ± 1.40 8.10 ± 0.99 8.08 ± 1.22 0.0040 0.9962
Haemoglobin (g/L) 129.30 ± 8.07 128.80 ± 9.50 129.30 ± 11.98 0.0050 0.9950
Platelets (× 109/L) 466.20 ± 45.31 481.80 ± 64.36 466.80 ± 63.64 0.1379 0.8723
  1. Crocin50 Crocin administered at 50 mg/kg, Crocin100 crocin administered at 100 mg/kg, ALT alanine aminotransferase, AST aspartate aminotransferase, TBIL total bilirubin, DBIL direct bilirubin, IBIL indirect bilirubin, TP total protein,ALB albumin, ALP alkaline phosphatase, CRE creatinine, BUN blood urea nitrogen
  2. * P < 0.05 versus control