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Fig. 3 | Parasites & Vectors

Fig. 3

From: Blood glucose promotes dengue virus infection in the mosquito Aedes aegypti

Fig. 3

AKT and TOR pathways are essential for DENV replication and transmission in Aedes aegypti. Three-day-old female mosquitoes were injected with dsRNA for LacZ (dsLacZ), AaTOR (dsTOR), or AaAKT (dsAKT) 3 days prior to the consumption of DENV infectious blood meals (1 × 107 pfu/ml) containing 0.1% glucose. a Nine days after infectious blood meal consumption, the viral titers of individual mosquitoes were quantified using a plaque assay. Numbers denotes total number of mosquitoes examined. b Nine days after infectious blood meal consumption, saliva was collected from pools of hundreds of mosquitoes and quantified using a plaque assay. All examined groups were demonstrated to be statistically significant using unpaired t-test; *P < 0.05, **P < 0.01. Data shown are from three independent biological cohorts and are presented as the mean ± SEM

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