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Table 1 Cytotoxicity and anti-MAYV activity of punicalagin and ethanol extract of pomegranate

From: Virucidal and antiviral activities of pomegranate (Punica granatum) extract against the mosquito-borne Mayaro virus

Substance

CC50a

IC50b

IS50c

RPd

Pomegranate ethanol extract

590.8 ± 17.7

12.3 ± 0.4

48

6

Punicalagin

425 ± 12.8

29.9 ± 0.9

14

1.75

Ribavirin

523.1 ± 10.5

62.5 ± 4.4

8

–

  1. a50% cytotoxic concentration
  2. b50% inhibitory concentration of viral replication
  3. cSelectivity index = CC50/IC50
  4. dRelative potency = IS50(substance)/IS50(ribavirin)
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Parasites & Vectors

ISSN: 1756-3305

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