Assessing the anti-resistance potential of public health vaporizer formulations and insecticide mixtures with pyrethroids using transgenic Drosophila lines

Table 1 Bioassay responses and resistance levels of transgenic Drosophila lines against K-Othrine, Fludora^® Fusion, and Clothianidin 70 WG in larval feeding bioassays

Genotype	K-Othrine	Equivalent^c deltamethrin	RR^b	Fludora fusion	Equivalent^c deltamethrin	Equivalent^c clothianidin	RR^b	Clothianidin 70WG	Equivalent^c clothianidin	RR^b
Genotype	LC50^a	LC50^a	RR^b	LC50^a	LC50^a	LC50^a	RR^b	LC50^a	LC50^a	RR^b
HR-J28	3.16 (2.76–3.52)	0.79 (0.69–0.88)	1	0.052 (0.02–0.08)	0.0033 (0.001–0.005)	0.026 (0.011–0.043)	1	0.039 (0.034–0.043)	0.027 (0.024–0.03)	1
L1014F;HR	15.008 (12.71–17.51)	3.752 (3.18–4.38)	4.74	0.228 (0.18–0.27)	0.0140 (0.011–0.017)	0.114 (0.09–0.137)	4.38	0.111 (0.093–0.131)	0.078 (0.065–0.092)	2.89
V1016G;HR-9J28	40.58 (32.05–52.99)	10.145 (8.01–13.25)	12.84	0.058 (0.05–0.07)	0.0036 (0.003–0.004)	0.029 (0.025–0.033)	1.12	0.059 (0.054–0.063)	0.041 (0.038–0.044)	1.52
L1014F;HR-6BQ23	48.76 (29.77–91.70)	12.191 (7.45–22.93)	15.43	0.348 (0.30–0.40)	0.0220 (0.019–0.025)	0.174 (0.15–0.198)	6.69	0.191 (0.169–0.213)	0.134 (0.118–0.149)	4.96

^aLethal concentration (95% confidence interval) in parts per million (ppm)
^bResistance ratio (RR), compared to HR-J28
^cEquivalent stands for the respective amount of active insecticide ingredient in each pesticide formulation

ISSN: 1756-3305