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Table 1 Time trend analysis of visceral leishmaniasis for eight epidemic provinces in China, 2004–2019

From: Epidemiological features and spatial–temporal distribution of visceral leishmaniasis in mainland China: a population-based surveillance study from 2004 to 2019

Areas

Number of cases 2004–2019

Number of deaths 2004–2019

Annual mean incidence (per 100,000 people)

Incidence rate ratio

Segmented period

Entire period

2004–2019

2004–2017

2018–2019

Period

APC (95% CI)

Trend

AAPC (95% CI)

Trend

Gansu

1605

3

0.3856

0.4115

0.2045

0.4970

2004–2009

13.7479 (− 1.1359, 30.8723)

Stable

− 3.8924 (− 8.6458, 1.1084)

Stable

2009–2019

− 11.6584* (− 15.8681, − 7.2382)

Decrease

Hebei

8

0

0.0007

0.0005

0.0020

4.0000

2004–2019

89.4744* (20.1610, 198.7704)

Increase

89.4744* (20.1610, 198.7704)

Increase

Henan

19

0

0.0012

0.0007

0.0052

7.4286

2004–2019

118.0616* (43.1933, 232.0749)

Increase

118.0616* (43.1933, 232.0749)

Increase

Inner Mongolia

10

0

0.0026

0.0030

0.0000

0.0000

2004–2019

− 48.6959* (− 70.2517, − 11.5207)

Decrease

− 48.6959* (− 70.2517, − 11.5207)

Decrease

Shanxi

144

0

0.0244

0.0109

0.1195

10.9633

2004–2019

76.9637* (20.9169, 158.9890)

Increase

76.9637* (20.9169, 158.9890)

Increase

Shaanxi

136

0

0.0223

0.0144

0.0775

5.3819

2004–2019

25.3849* (19.9419, 31.0750)

Increase

25.3849* (19.9419, 31.0750)

Increase

Sichuan

593

5

0.0453

0.0496

0.0150

0.3024

2004–2010

8.1144 (− 4.8372, 22.8286)

Stable

− 8.6387* (− 13.8294, − 3.1353)

Decrease

2010–2019

− 18.3390* (− 23.7769, − 12.5132)

Decrease

Xinjiang

2250

3

0.6547

0.7423

0.0421

0.0567

2004–2016

− 3.0432 (− 16.6773, 12.8219)

Stable

− 22.7750* (− 40.0054, -0.5961)

Decrease

2016–2019

− 68.9203 (− 91.3710, 11.9422)

Stable

Overall

4877

13

0.0228

0.0243

0.0123

0.5062

2004–2019

− 4.2564* (− 8.0856, − 0.2677)

Decrease

− 4.2564* (− 8.0856, − 0.2677)

Decrease

  1. APC annual percentage change, AAPC average annual percentage change
  2. *P value < 0.05