Skip to main content
Fig. 2 | Parasites & Vectors

Fig. 2

From: Immune reactivity and host modulatory roles of two novel Haemonchus contortus cathepsin B-like proteases

Fig. 2

Three-dimensional modeling of H. contortus cathepsin B-like proteases Hc-CBP-1 and Hc-CBP-2. The 3D models of Hc-CBP-1 and Hc-CBP-2 were generated using the x-ray crystallographic structure of mature cathepsin B from the genus Rattus using SWISS-MODEL. The catalytic triad residues Cys119 (a) and Cys112 (b) were in the left domain and His289 (a) and His293 (b) and Asn309 (a) and Asn312 (b) in the right domain. On the right panel, the surface-exposed loops specific to H. contortus are highlighted in green. The residues delimitating the loops—Leu73-Pro80, Asn182-Pro193, Arg221-Asp233 for Hc-CBP-1 and between Arg-74-Asp89, Tyr186-Pro194 and Cys221-Thr238 for Hc-CBP-2—are highlighted in green using Microsoft Paint (Microsoft Corporation, Redmond, WA)

Back to article page

Parasites & Vectors

ISSN: 1756-3305

Contact us